Description

4-[(1,1-Dimethylprop-2-Ynyl)Oxy]Benzonitrile is a specialized organic compound featuring a benzonitrile core functionalized with a propargyl ether group. This unique molecular architecture makes it a valuable building block and key intermediate in advanced organic synthesis. It is primarily utilized by pharmaceutical, agrochemical, and material science research and development teams for constructing complex molecules and exploring novel chemical entities.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for molecules requiring a propargyl ether or cyanoaryl moiety.
• Agrochemical Synthesis: Serves as a precursor in the development of modern pesticides, herbicides, and plant growth regulators.
• Material Science Research: Used in the synthesis of specialty polymers, liquid crystals, and advanced organic electronic materials due to its rigid aromatic and alkyne functionalities.
• Chemical Biology & Proteomics: Acts as a click chemistry handle (via the alkyne group) for bioconjugation, labeling, and activity-based protein profiling studies.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, cycloadditions, and other transformations to create complex heterocycles and functionalized aromatics.

Basic Information

Product Name	4-[(1,1-Dimethylprop-2-Ynyl)Oxy]Benzonitrile
CAS No.	33143-92-9
Molecular Formula	C12H11NO
Molecular Weight	185.22 g/mol
Synonyms	4-(1,1-Dimethyl-2-propynyloxy)benzonitrile; 4-(2,2-Dimethyl-3-butynyloxy)benzonitrile; 4-(3,3-Dimethylbut-1-yn-1-yloxy)benzonitrile; p-[(1,1-Dimethyl-2-propynyl)oxy]benzonitrile; Benzonitrile, 4-[(1,1-dimethyl-2-propynyl)oxy]-; 33143-92-9; 4-(1,1-Dimethylpropargyloxy)benzonitrile
EINECS	Contact for details

Quality Control

Our 4-[(1,1-Dimethylprop-2-Ynyl)Oxy]Benzonitrile is produced under a strict quality management system. Every batch undergoes rigorous analytical testing to ensure high purity and consistent performance as a synthesis intermediate. Standard quality verification includes chromatographic purity assay and identity confirmation. Certificates of Analysis (COA) documenting batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (typically 15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.