Description

4-(Prop-2-Ynyloxy)Benzonitrile is a versatile organic intermediate featuring a benzonitrile core functionalized with a propargyl ether group. This unique molecular structure, combining an electron-withdrawing nitrile with a reactive alkyne moiety, makes it a valuable building block for advanced chemical synthesis. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecules, particularly in click chemistry and cross-coupling reactions.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially those requiring alkyne-azide cycloaddition (click chemistry) for bioconjugation or polymer modification.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and plant growth regulators that incorporate the benzonitrile pharmacophore.
• Material Science & Polymer Chemistry: Serves as a monomer or cross-linking agent for creating specialty polymers, resins, and advanced materials with tailored thermal or mechanical properties.
• Liquid Crystal & OLED Materials: Acts as a precursor in the development of organic electronic materials, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Organic Synthesis & Catalysis: A valuable substrate in palladium-catalyzed Sonogashira and other cross-coupling reactions to create complex aromatic systems for further functionalization.
• Research & Development: Essential compound in academic and industrial R&D labs for exploring new synthetic methodologies and creating novel chemical entities for screening.

Basic Information

Product Name	4-(Prop-2-Ynyloxy)Benzonitrile
CAS No.	33143-80-5
Molecular Formula	C10H7NO
Molecular Weight	157.17 g/mol
Synonyms	4-(2-Propynyloxy)benzonitrile; 4-(Prop-2-yn-1-yloxy)benzonitrile; p-(Prop-2-yn-1-yloxy)benzonitrile; 4-(Propargyloxy)benzonitrile; Benzonitrile, 4-(2-propynyloxy)-; 4-Cyano phenyl propargyl ether; Propargyl 4-cyanophenyl ether
EINECS	Contact for details

Quality Control

Our 4-(Prop-2-Ynyloxy)Benzonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flames. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.