Description

3-Trifluoromethylisoxazole is a high-value fluorinated heterocyclic building block essential for advanced chemical synthesis. Its unique structure, featuring a reactive isoxazole ring and a stable trifluoromethyl group, makes it a critical intermediate for introducing fluorine motifs into target molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries to develop novel active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly for incorporating the metabolically stable trifluoromethyl group.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides where the fluorine moiety improves biological activity and environmental stability.
• Material Science Research: Acts as a precursor for specialty polymers, liquid crystals, and electronic chemicals that benefit from fluorine's unique properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, cycloadditions, and other transformations to construct complex heterocyclic frameworks.
• Chemical Biology Probes: Useful for labeling and modifying biomolecules in diagnostic and research applications.

Basic Information

Product Name	3-Trifluoromethylisoxazole
CAS No.	32990-29-7
Molecular Formula	C4H2F3NO
Molecular Weight	137.06 g/mol
Synonyms	3-(Trifluoromethyl)-1,2-oxazole; 3-(Trifluoromethyl)isoxazole; 3-Trifluoromethyl-1,2-oxazole; Isoxazole, 3-(trifluoromethyl)-; 3-Trifluoromethylisoxazole; 3-CF3-Isoxazole
EINECS	Contact for details

Quality Control

Our 3-Trifluoromethylisoxazole is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and open flames. Due to its high volatility, ensure containers are kept tightly sealed when not in use. Recommended storage temperature: 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.