Description

Mast Cell Degranulating Peptide is a synthetic bioactive peptide known for its potent ability to induce the release of histamine and other mediators from mast cells. This compound is a critical research tool for studying allergic responses, inflammatory pathways, and mast cell biology. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies focused on immunology and drug discovery.

Application

• Immunological Research: A key reagent for in vitro and in vivo studies of mast cell activation, degranulation mechanisms, and allergic reactions.
• Drug Discovery & Screening: Used to establish assay systems for evaluating potential anti-allergic, anti-inflammatory, or mast cell-stabilizing compounds.
• Inflammation Models: Employed to induce controlled inflammatory responses in animal models for preclinical research.
• Biochemical Studies: Facilitates the investigation of signal transduction pathways and receptor interactions involved in immune cell function.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in peptide synthesis and characterization.

Basic Information

Product Name	Mast Cell Degranulating Peptide
CAS No.	32908-73-9
Molecular Formula	C₁₀₀H₁₄₈N₃₀O₂₈S₂
Molecular Weight	2286.6 g/mol
Synonyms	MCD Peptide; Mastoparan; Polistes Mastoparan; Mast Cell Degranulating Factor; Peptide 401; Apamin; Wasp Venom Peptide; Vespula Mastoparan
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch of Mast Cell Degranulating Peptide is characterized using advanced analytical techniques to confirm identity, purity, and biological activity. Certificates of Analysis (COA) detailing purity by HPLC, amino acid analysis, and mass spectrometry are available upon request. We adhere to cGMP guidelines for the production of research-grade bioactive peptides.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Composition	Within ±10% of theoretical
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80%
Biological Activity	Assay-dependent; COA provided

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.