Description

2-Propynenitrile, 3-(1-Hydroxycyclohexyl)- (9Ci) is a specialized organic nitrile compound featuring a propargyl nitrile moiety attached to a hydroxycyclohexyl group. This unique molecular architecture makes it a valuable and versatile building block in advanced organic synthesis and pharmaceutical research. It is primarily sought after by R&D chemists and process development scientists in the fine chemical and pharmaceutical industries for constructing complex molecular frameworks.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring propargyl or cyano functional groups.
• Agrochemical Synthesis: Used in the research and development of advanced crop protection agents and herbicides.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of specialty polymers and advanced materials.
• Organic Synthesis Building Block: Employed in click chemistry reactions, such as copper-catalyzed azide-alkyne cycloaddition (CuAAC), due to its alkyne functionality.
• Ligand and Catalyst Development: Utilized in the preparation of novel ligands and organometallic catalysts for asymmetric synthesis.
• Chemical Biology Probes: Functions as a tagging or labeling reagent in bioconjugation and probe development for studying biological systems.

Basic Information

Product Name	2-Propynenitrile, 3-(1-Hydroxycyclohexyl)- (9Ci)
CAS No.	32837-89-1
Molecular Formula	C9H11NO
Molecular Weight	149.19 g/mol
Synonyms	3-(1-Hydroxycyclohexyl)-2-propynenitrile; 1-(Cyanomethylidene)cyclohexanol; 1-(Cyanomethylene)cyclohexanol; 1-Hydroxy-1-(2-propynylidene)cyclohexane carbonitrile; 3-(1-Hydroxycyclohexyl)propiolonitrile; 1-(2-Propynylidene)cyclohexanol-1-carbonitrile
EINECS	Contact for details

Quality Control

Our 2-Propynenitrile, 3-(1-Hydroxycyclohexyl)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flames. Due to the reactive nature of the nitrile and alkyne groups, it is recommended to store under an inert atmosphere for long-term stability and to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.