Description

n-Acetylprocainamide is a key pharmaceutical intermediate and metabolite of the antiarrhythmic drug procainamide. This compound is of significant importance in the research and development of cardiac therapeutics and for conducting detailed pharmacokinetic and metabolic studies. It serves as a critical reference standard and building block for pharmaceutical manufacturers, analytical laboratories, and academic research institutions focused on cardiovascular medicine.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of specialized cardiac medications and for the development of novel therapeutic agents.
• Metabolite Reference Standard: Used as an analytical standard in bioanalytical laboratories for the quantification of procainamide and its metabolites in biological matrices (e.g., plasma, serum) during pharmacokinetic studies.
• Pharmacological Research: Employed in research to study the metabolism, efficacy, and potential toxicity profiles of procainamide and related compounds.
• Quality Control & Method Development: Essential for developing and validating analytical methods (HPLC, LC-MS) in pharmaceutical quality control laboratories to ensure drug purity and consistency.
• Clinical Diagnostics: May be utilized as a calibrator or control in diagnostic assays designed to monitor therapeutic drug levels in patients.

Basic Information

Product Name	n-Acetylprocainamide
CAS No.	32795-44-1
Molecular Formula	C15H23N3O2
Molecular Weight	277.36 g/mol
Synonyms	N-Acetylprocainamide; NAPA; Acecainide; Acetylprocainamide; 4-Amino-N-[2-(diethylamino)ethyl]-N-phenylbenzamide acetate; Procainamide N-acetate
EINECS	Contact for details

Quality Control

Our n-Acetylprocainamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical research and development. A detailed Certificate of Analysis (COA) providing purity, identity, and impurity profiles is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Loss on Drying	≤1.0%
Related Substances (HPLC)	Individual impurity ≤0.5% Total impurities ≤1.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.