Description

n-(Benzyloxycarbonyl)-L-Aspartic Acid Disodium Salt is a protected amino acid derivative widely used as a key building block in peptide synthesis and pharmaceutical research. This compound is essential for introducing the L-aspartic acid moiety into peptide chains while protecting the reactive side chain carboxyl group. It is primarily utilized by research institutions, pharmaceutical development labs, and fine chemical manufacturers engaged in the production of bioactive peptides, APIs, and complex organic molecules. The product is supplied as a high-purity reagent to ensure optimal performance in sensitive synthetic applications.

Application

• Solid-Phase Peptide Synthesis (SPPS): A crucial reagent for the controlled incorporation of aspartic acid into peptide sequences.
• Solution-Phase Peptide Synthesis: Used in classical peptide coupling reactions to construct specific peptide bonds.
• Pharmaceutical Intermediate: Serves as a building block in the synthesis of potential therapeutic peptides and protein-based drugs.
• Biochemical Research: Employed in studies of enzyme substrates, receptor ligands, and other biologically active compounds.
• Fine Chemical Synthesis: A versatile intermediate for creating complex organic molecules requiring protected amino acid functionality.
• Protecting Group Chemistry: The benzyloxycarbonyl (Cbz or Z) group provides orthogonal protection strategies in multi-step syntheses.

Basic Information

Product Name	n-(Benzyloxycarbonyl)-L-Aspartic Acid Disodium Salt
CAS No.	32791-63-2
Molecular Formula	C12H11NNa2O6
Molecular Weight	311.20 g/mol
Synonyms	Z-L-Aspartic Acid Disodium Salt; Cbz-L-Aspartic Acid Disodium Salt; N-Carbobenzoxy-L-aspartic Acid Disodium Salt; (S)-2-(((Benzyloxy)carbonyl)amino)butanedioic Acid Disodium Salt; L-Aspartic Acid, N-[(phenylmethoxy)carbonyl]-, Disodium Salt; Aspartic Acid, N-carboxy-, N-benzyl ester, Disodium Salt, L-; Benzyl N-[(1S)-1,2-dicarboxyethyl]carbamate Disodium Salt; Nα-Cbz-L-aspartic Acid Disodium Salt
EINECS	Contact for details

Quality Control

Our n-(Benzyloxycarbonyl)-L-Aspartic Acid Disodium Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the high standards required for research and synthesis. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming specifications for identity, purity, and related substances. We support compliance with relevant industry guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent absorption of atmospheric moisture, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation [α]D20	Contact for details
Water Content (KF)	≤5.0%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.