Description

3-(Difluoromethoxy)-1,1,2,2-Tetrafluoropropane is a specialized fluorinated organic compound, identified by CAS NO 32778-11-3. This chemical is valued for its unique combination of high volatility and fluorinated structure, making it a critical intermediate and solvent in advanced manufacturing processes. It is primarily sought after by R&D laboratories and industrial producers in the pharmaceutical, agrochemical, and specialty chemical sectors for applications requiring precise fluorination or inert, volatile media.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring difluoromethoxy or tetrafluoropropane motifs.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where the introduction of fluorine atoms enhances biological activity and environmental stability.
• Specialty Solvent: Acts as a high-volatility solvent for precision cleaning, deposition processes, or as a reaction medium in fluorochemistry.
• Chemical Research & Development: A valuable reagent for exploring new fluorination methodologies and creating novel fluorinated compounds in academic and industrial R&D settings.
• Electronic Chemicals: Potential use in the electronics industry for etching or cleaning applications due to its volatile and inert nature.
• Refrigerant & Propellant Blending Component: May be investigated as a component in next-generation, low-global-warming-potential (GWP) refrigerant or aerosol propellant blends.

Basic Information

Product Name	3-(Difluoromethoxy)-1,1,2,2-Tetrafluoropropane
CAS No.	32778-11-3
Molecular Formula	C4H3F6O
Molecular Weight	196.06 g/mol
Synonyms	1,1,2,2-Tetrafluoro-3-(difluoromethoxy)propane; 3-(Difluoromethoxy)-1,1,2,2-tetrafluoropropane; Propane, 3-(difluoromethoxy)-1,1,2,2-tetrafluoro-; HFE-356mmz2 (potential trade designation); HFO/CF/HFE Hybrid; Fluorinated ether; Difluoromethyl 2,2,3,3-tetrafluoropropyl ether
EINECS	Contact for details

Quality Control

Our 3-(Difluoromethoxy)-1,1,2,2-Tetrafluoropropane is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including Gas Chromatography (GC) and Nuclear Magnetic Resonance (NMR), to ensure high purity and consistent composition. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to guarantee compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile nature, store in a cool, well-ventilated area away from heat sources and open flames. Recommended storage temperature is between 2°C and 25°C. Keep container tightly sealed when not in use to prevent evaporation and potential moisture ingress.

Specification

Item	Specification
Appearance	Colorless clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Density (20°C)	~1.45 g/cm³
Boiling Point	~60-70°C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.