Description

Dapsone Hydroxylamine is a key pharmaceutical intermediate and chemical building block, primarily recognized for its role in the synthesis of dapsone and related sulfone compounds. Its importance lies in providing a reactive hydroxylamine functional group, enabling critical chemical transformations in the production of active pharmaceutical ingredients (APIs). This compound is essential for manufacturers and research institutions in the pharmaceutical, agrochemical, and fine chemical sectors who require high-purity intermediates for complex synthesis.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of Dapsone (4,4'-diaminodiphenyl sulfone), an important API used in the treatment of leprosy, dermatitis herpetiformis, and certain dermatological conditions.
• Chemical Synthesis Building Block: Utilized in organic synthesis to introduce the hydroxylamine moiety into target molecules for the development of novel sulfone-based compounds.
• Research & Development: Serves as a standard reagent in medicinal chemistry research for exploring new antimicrobial and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the development pathway for certain sulfone-based pesticides and fungicides.
• Fine Chemical Production: Employed in the manufacture of specialized dyes, pigments, and other performance chemicals where the sulfone structure is required.

Basic Information

Product Name	Dapsone Hydroxylamine
CAS No.	32695-27-5
Molecular Formula	C12H12N2O2S
Molecular Weight	248.30 g/mol
Synonyms	4-Amino-4'-hydroxyaminodiphenyl sulfone; N-Hydroxy-4,4'-sulfonyldianiline; 4-(4-Aminophenyl)sulfonylphenylhydroxylamine; DDS hydroxylamine; Dapsone N-hydroxy derivative; 4-Amino-4'-(hydroxyamino)diphenyl sulfone; Bis(4-aminophenyl) sulfone hydroxylamine
EINECS	Contact for details

Quality Control

Our Dapsone Hydroxylamine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting standards for pharmaceutical intermediate applications. Certificates of Analysis (COA) detailing purity, related substances, and residual solvents are provided with every shipment to guarantee traceability and compliance with your internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation to maintain optimal purity and stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.