Description

3-Acetylamino-2,4,6-Triiodo-5-[2-(Methylamino)-2-Oxoethyl]Benzoic Acid is a high-purity, iodinated organic compound primarily used as a key intermediate in the synthesis of advanced pharmaceutical agents. Its value lies in its precise molecular structure, which is critical for producing high-contrast, non-ionic X-ray contrast media used in diagnostic imaging. This compound is essential for manufacturers in the pharmaceutical and fine chemical industries who require reliable, high-quality building blocks for complex drug synthesis. We supply this material with a focus on batch-to-batch consistency and stringent quality control to meet the demanding standards of global API production.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of non-ionic, iodinated X-ray contrast media (e.g., Iopamidol, Iohexol analogs).
• Diagnostic Imaging Agent Precursor: Used in the research and development of next-generation contrast agents for computed tomography (CT) and angiography.
• Fine Chemical Synthesis: Serves as a specialized intermediate for creating complex, triiodobenzene-derived molecules in organic chemistry.
• API (Active Pharmaceutical Ingredient) Manufacturing: Employed in controlled GMP environments for the production of final drug substances.
• Biomedical Research: Utilized in academic and industrial R&D for studying radiopaque compounds and their biological interactions.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development and quality control laboratories.

Basic Information

Product Name	3-Acetylamino-2,4,6-Triiodo-5-[2-(Methylamino)-2-Oxoethyl]Benzoic Acid
CAS No.	32637-73-3
Molecular Formula	C12H11I3N2O4
Molecular Weight	651.94 g/mol
Synonyms	5-[N-Methylacetamido]-2,4,6-triiodoisophthalamic acid; 5-Acetamido-2,4,6-triiodo-N-methylisophthalamic acid; Iopamidol Intermediate; AD-01; Iohexol Related Compound; 2,4,6-Triiodo-5-(N-methylacetamido)isophthalamic Acid; 3-Acetamido-2,4,6-triiodo-5-(N-methylcarbamoylmethyl)benzoic Acid
EINECS	Contact for details

Quality Control

Every batch of 3-Acetylamino-2,4,6-Triiodo-5-[2-(Methylamino)-2-Oxoethyl]Benzoic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for pharmaceutical intermediate use. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for each lot. Our quality commitment aligns with ICH guidelines and supports our customers' needs for regulatory filings (e.g., DMF, CMC sections).

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.