Description

4-(T-Butoxy)Phenylacetylene is a specialized organic building block featuring a terminal alkyne group protected by a tert-butoxy substituent on the aromatic ring. This compound is valued for its role as a versatile intermediate in advanced organic synthesis, particularly in cross-coupling reactions like Sonogashira and Click chemistry. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries developing active ingredients, ligands, and functional polymers.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and plant growth regulators.
• Material Science & Polymer Chemistry: Serves as a monomer or cross-linker for producing specialty polymers, conductive materials, and liquid crystals.
• Organic Synthesis & Research: A crucial reagent in Sonogashira coupling, Huisgen cycloaddition (Click Chemistry), and other palladium-catalyzed reactions.
• Ligand & Catalyst Development: Used to synthesize advanced ligands for catalysis and molecular recognition applications.
• Fine Chemical Production: Intermediate in the manufacture of dyes, flavors, and fragrances.

Basic Information

Product Name	4-(T-Butoxy)Phenylacetylene
CAS No.	32569-86-1
Molecular Formula	C12H14O
Molecular Weight	174.24 g/mol
Synonyms	1-(tert-Butoxy)-4-ethynylbenzene; 4-(tert-Butoxy)phenylacetylene; 4-tert-Butoxyphenylacetylene; p-(tert-Butoxy)phenylacetylene; 1-Ethynyl-4-(tert-butoxy)benzene; 4-Ethynylphenyl tert-butyl ether; TBPA
EINECS	Contact for details

Quality Control

Our 4-(T-Butoxy)Phenylacetylene is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon to maximize stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.