Description

Aminobutane Bisphosphonate is a high-purity, nitrogen-containing bisphosphonate compound, also known by its CAS number 32545-60-1. This chemical is valued for its strong chelating and bone-targeting properties, making it a critical intermediate in advanced pharmaceutical and material science applications. It is primarily required by research institutions and manufacturers in the pharmaceutical, biomedical, and specialty chemical sectors for developing novel therapeutics and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel bisphosphonate drugs targeting bone disorders such as osteoporosis and Paget's disease.
• Biomedical Research: Used in biochemical studies to investigate bone metabolism and as a molecular probe for studying hydroxyapatite binding.
• Material Science: Acts as a functional ligand or surface modifier for creating biocompatible coatings on medical implants and nanoparticles.
• Chelating Agent: Employed in analytical chemistry and water treatment processes for its ability to sequester divalent metal ions like calcium and magnesium.
• Dental Material Formulation: A component in advanced formulations for dental cements and adhesives to enhance bonding to tooth mineral.

Basic Information

Product Name	Aminobutane Bisphosphonate
CAS No.	32545-60-1
Molecular Formula	C4H13NO6P2
Molecular Weight	233.10 g/mol
Synonyms	4-Amino-1-hydroxybutylidene-1,1-bisphosphonic acid; Alendronic Acid Impurity; 4-Amino-1-hydroxybutane-1,1-diyldiphosphonic Acid; ABP; Aminobutylidene Bisphosphonate; Fosamax Related Compound; 4-Amino-1-hydroxybutylidene-1,1-diphosphonic Acid; Alendronate Intermediate
EINECS	Contact for details

Quality Control

Our Aminobutane Bisphosphonate is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a low-humidity environment to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.