Description

(6R-Trans)-3-(Acetoxymethyl)-8-Oxo-7-(1H-Tetrazol-1-Ylacetamido)-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid is a key advanced pharmaceutical intermediate, specifically a cephalosporin nucleus derivative. It matters as a critical building block in the synthesis of modern, broad-spectrum cephalosporin antibiotics, enabling the development of more effective antimicrobial agents. This high-purity compound is essential for pharmaceutical manufacturers and research institutions focused on antibiotic development, API synthesis, and advanced pharmaceutical chemistry.

Application

• Active Pharmaceutical Ingredient (API) Synthesis: A crucial intermediate in the production of third and fourth-generation cephalosporin antibiotics.
• Pharmaceutical Research & Development: Used in medicinal chemistry for the design and synthesis of novel β-lactam antibiotic candidates.
• Process Chemistry & Scale-Up: Serves as a key starting material for optimizing synthetic routes and scaling up antibiotic production.
• Reference Standard: Employed as a high-purity analytical standard for quality control and regulatory testing of finished antibiotic products.
• Biochemical Studies: Utilized in research investigating bacterial resistance mechanisms and the structure-activity relationships of β-lactam drugs.

Basic Information

Product Name	(6R-Trans)-3-(Acetoxymethyl)-8-Oxo-7-(1H-Tetrazol-1-Ylacetamido)-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid
CAS No.	32510-61-5
Molecular Formula	C15H15N7O6S
Molecular Weight	421.39 g/mol
Synonyms	7β-[(1H-Tetrazol-1-yl)acetamido]-3-(acetoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid; 7-TACA; 7β-[(1H-Tetrazol-1-yl)acetamido]cephalosporanic Acid Derivative; Cephalosporin 7-TACA Intermediate; (6R,7R)-3-(Acetoxymethyl)-8-oxo-7-[(1H-tetrazol-1-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid
EINECS	Contact for details

Quality Control

Our (6R-Trans)-3-(Acetoxymethyl)-8-Oxo-7-(1H-Tetrazol-1-Ylacetamido)-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid is manufactured under strict quality management systems. The product undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural integrity suitable for pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each batch to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.