Description

N,n-Dimethylformamide (Carbonyl-13C1) is a stable isotope-labeled analog of the universal polar aprotic solvent, where the carbonyl carbon is enriched with the 13C isotope. This specific labeling is critical for advanced analytical and research applications, providing a non-radioactive tracer for mechanistic studies and quantitative analysis. It is an essential reagent for scientists and manufacturers in pharmaceutical research, NMR spectroscopy, and metabolic pathway tracing who require high isotopic purity and chemical consistency.

Application

• NMR Spectroscopy & Analytical Standards: Serves as an internal standard, chemical shift reference, and solvent for complex structure elucidation in nuclear magnetic resonance studies.
• Pharmaceutical R&D & Metabolism Studies: Used as a labeled precursor or solvent in the synthesis and tracing of drug metabolites to understand absorption, distribution, metabolism, and excretion (ADME).
• Mechanistic Organic Chemistry Research: Enables detailed investigation of reaction mechanisms and kinetics by tracking the fate of the carbonyl carbon atom.
• Quantitative Mass Spectrometry (MS): Employed in the development of stable isotope dilution assays for highly accurate quantification of analytes in complex matrices.
• Specialty Chemical Synthesis: Acts as a labeled building block for the synthesis of more complex 13C-labeled compounds for research and diagnostic purposes.

Basic Information

Product Name	N,n-Dimethylformamide (Carbonyl-13C1)
CAS No.	32488-43-0
Molecular Formula	C³H₇N¹³CO
Molecular Weight	74.08 g/mol
Synonyms	DMF-13C1; [13C]Formic acid dimethylamide; N,N-Dimethyl[13C]formamide; [Carbonyl-13C]-N,N-Dimethylformamide; 13C-Labeled DMF; Dimethyl[13C]formamide; (13C)Dimethylformamide; N,N-Dimethylformamide-13C
EINECS	Contact for details

Quality Control

Every batch of our N,n-Dimethylformamide (Carbonyl-13C1) is produced and analyzed under strict quality management protocols to ensure exceptional isotopic and chemical purity. We provide comprehensive Certificates of Analysis (COA) detailing key parameters such as isotopic enrichment (13C atom %), chemical purity by GC/NMR, and solvent content. Our quality commitment supports compliance with the rigorous standards required for research and analytical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure containers are sealed immediately after use to prevent absorption of atmospheric moisture, which can affect purity and isotopic integrity.

Specification

Item	Specification
Appearance	Colorless clear liquid
Identification (IR/NMR)	Conforms to structure
Isotopic Enrichment (13C atom %)	≥ 99%
Chemical Purity (GC)	≥ 99.5%
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.