Description

2-Methyl-2-(4-Trifluoromethyl-Phenyl)-Propionitrile is a specialized organic nitrile building block featuring a trifluoromethylphenyl group. This compound is valued for its unique molecular structure, which combines lipophilicity and electronic properties imparted by the fluorine atoms, making it a critical intermediate in advanced synthetic chemistry. It is primarily sought after by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for constructing complex active molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorine-containing compounds used in electronic display technologies and organic light-emitting diodes.
• Advanced Polymer Modifier: Incorporated into specialty polymers to alter surface properties, improve chemical resistance, and adjust refractive index.
• Organic Synthesis Reagent: Employed in palladium-catalyzed cross-coupling reactions, cyanoalkylation, and other fine chemical transformations in R&D laboratories.
• Fluorine Chemistry Research: A valuable compound for academic and industrial research exploring the effects of fluorinated groups on molecular reactivity and physicochemical properties.

Basic Information

Product Name	2-Methyl-2-(4-Trifluoromethyl-Phenyl)-Propionitrile
CAS No.	32445-87-7
Molecular Formula	C11H10F3N
Molecular Weight	213.20 g/mol
Synonyms	α,α-Dimethyl-4-(trifluoromethyl)benzeneacetonitrile; 2-(4-(Trifluoromethyl)phenyl)-2-methylpropionitrile; 4-(Trifluoromethyl)phenylacetonitrile, α,α-dimethyl-; 2-Methyl-2-[4-(trifluoromethyl)phenyl]propanenitrile; p-(Trifluoromethyl)benzeneacetonitrile, α,α-dimethyl-; 2-(p-Trifluoromethylphenyl)isobutyronitrile; 2-(4-Trifluoromethylphenyl)-2-methylpropionitrile
EINECS	Contact for details

Quality Control

Our 2-Methyl-2-(4-Trifluoromethyl-Phenyl)-Propionitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high chemical purity and identity. We provide Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability, consistency, and reliability for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and oxidizing agents. Recommended storage temperature is between 15°C and 25°C. The product is stable under these conditions for extended periods.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.