Description

1-(Pyridine-3-Carbonyl)Piperazine Dihydrochloride is a high-purity, versatile pharmaceutical intermediate and organic building block. This compound is valued for its role in the synthesis of complex molecules, particularly in medicinal chemistry research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking reliable, high-quality synthetic precursors.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to create novel compound libraries for biological screening.
• Ligand Synthesis: Serves as a precursor for creating complex ligands used in catalysis and metal-organic frameworks (MOFs).
• Agrochemical Development: Employed in the research and synthesis of novel crop protection agents and pesticides.
• Chemical Biology Probes: Useful for constructing molecular probes to study enzyme function and biological pathways.
• Academic & Institutional R&D: A valuable reagent for universities and research institutes conducting synthetic organic chemistry and drug discovery projects.

Basic Information

Product Name	1-(Pyridine-3-Carbonyl)Piperazine Dihydrochloride
CAS No.	32422-95-0
Molecular Formula	C10H14N3O·2HCl
Molecular Weight	279.16 g/mol
Synonyms	1-(Nicotinoyl)piperazine dihydrochloride; 1-(3-Pyridinylcarbonyl)piperazine dihydrochloride; 3-(Piperazine-1-carbonyl)pyridine dihydrochloride; Nicotinic acid piperazide dihydrochloride; Piperazine, 1-(3-pyridinecarbonyl)-, dihydrochloride; N-(Piperazin-1-yl)pyridine-3-carboxamide dihydrochloride
EINECS	Contact for details

Quality Control

Our 1-(Pyridine-3-Carbonyl)Piperazine Dihydrochloride is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.