Description

Bunaftine CAS NO 32421-46-8 is a high-purity pharmaceutical intermediate and research chemical belonging to the class of antiarrhythmic agents. It is a critical building block in the synthesis of specialized active pharmaceutical ingredients (APIs) for cardiovascular research and development. This compound is essential for pharmaceutical manufacturers, R&D laboratories, and academic institutions focused on developing and testing new therapeutic agents for cardiac conditions.

Application

• Pharmaceutical Intermediate: Primary use as a key synthetic precursor in the production of antiarrhythmic drugs.
• Cardiovascular Research: Used in biochemical and pharmacological studies to investigate mechanisms of cardiac ion channel modulation.
• API Development: Serves as a critical starting material or intermediate in the multi-step synthesis of novel Active Pharmaceutical Ingredients (APIs).
• Reference Standard: Employed as an analytical standard in quality control (QC) and quality assurance (QA) laboratories for method development and validation.
• Preclinical Studies: Utilized in *in vitro* and *in vivo* models to assess efficacy, pharmacokinetics, and safety profiles of new chemical entities.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	Bunaftine
CAS No.	32421-46-8
Molecular Formula	C24H35NO3
Molecular Weight	385.55 g/mol
Synonyms	Bunaftine; Bunaftinum; 2-Butyl-3-[(4-(3-(di-n-butylamino)propoxy)benzoyl]benzofuran; Benzofuran, 2-butyl-3-[[4-[3-(dibutylamino)propoxy]benzoyl]-; Meregon; Bunaphtide; Bunaftina; Bunaftinum [INN-Latin]; Bunaftine [INN-French]
EINECS	251-014-5

Quality Control

Our Bunaftine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with specifications for Assay (HPLC), related substances, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.