Description

4-Fluoro-2-Methylthiophene is a high-purity fluorinated heterocyclic building block essential for advanced organic synthesis. This compound matters for its role in introducing both fluorine and thiophene motifs into target molecules, enabling the fine-tuning of electronic properties, lipophilicity, and metabolic stability. It is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in central nervous system (CNS) and anti-infective therapies.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom enhances biological activity and environmental stability.
• Organic Electronic Materials: Serves as a precursor for conjugated polymers and small molecules used in organic light-emitting diodes (OLEDs), field-effect transistors (OFETs), and solar cells.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Fluorine Chemistry Research: A valuable reagent for academic and industrial research exploring new fluorination methodologies and structure-activity relationships (SAR).
• Liquid Crystal and Display Technology: Used in the synthesis of fluorinated components for liquid crystal mixtures, improving display performance.

Basic Information

Product Name	4-Fluoro-2-Methylthiophene
CAS No.	32415-56-8
Molecular Formula	C5H5FS
Molecular Weight	116.16 g/mol
Synonyms	2-Methyl-4-fluorothiophene; 4-Fluoro-2-methylthiophene; 4-Fluoro-2-methylthiofuran; 2-Methyl-4-fluorothiofuran; 4-Fluoro-2-methyl-1-thia-2,4-cyclopentadiene; 32415-56-8; 4-Fluoro-2-methylthiophene (stabilized)
EINECS	Contact for details

Quality Control

Our 4-Fluoro-2-Methylthiophene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and batch-to-batch consistency for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Individual ≤ 0.5%, Total ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.