Description

tert-Butyldimethylphosphine CAS NO 32376-17-3 is a highly versatile organophosphorus compound, prized for its role as a strong electron-donating ligand in transition metal catalysis. Its primary value lies in enabling highly efficient and selective chemical transformations, particularly in cross-coupling reactions and hydrogenation processes. This chemical is essential for research and development chemists, process engineers, and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise control over reaction pathways.

Application

• Catalyst Ligand in Pharmaceutical Intermediates: A key component in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Negishi) for constructing complex carbon-carbon bonds in active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development and scale-up of novel pesticides and herbicides, where its ligand properties enhance catalyst activity and selectivity.
• Fine Chemical and Specialty Material Production: Facilitates hydrogenation, hydroformylation, and other catalytic processes in the synthesis of flavors, fragrances, and electronic materials.
• Academic and Industrial R&D: Serves as a fundamental tool for exploring new catalytic systems and methodologies in synthetic organic and organometallic chemistry.
• Polymerization Catalysis: Employed as a co-catalyst or ligand in the synthesis of specialized polymers with controlled architectures.

Basic Information

Product Name	tert-Butyldimethylphosphine
CAS No.	32376-17-3
Molecular Formula	C6H15P
Molecular Weight	118.16 g/mol
Synonyms	tert-Butyldimethylphosphane; (Dimethyl)(tert-butyl)phosphine; Phosphino-tert-butane, dimethyl-; t-BuMe2P; P(t-Bu)Me2; 2-Methyl-2-propyldimethylphosphine; tert-Butyl-dimethyl-phosphine; DTBP
EINECS	Contact for details

Quality Control

Our tert-Butyldimethylphosphine is produced and handled under stringent quality protocols to ensure batch-to-batch consistency and high purity, critical for sensitive catalytic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality management system adheres to cGMP principles where applicable, supporting our commitment to supply reliability for your most demanding synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Due to its sensitivity to oxidation, this material must be stored under an inert atmosphere (argon or nitrogen). Recommended storage temperature is 2-8°C. Keep the container in a cool, dry, well-ventilated place, away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC)	≥ 95.0%
Purity (NMR)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.