Description

Z-Ala-His-Ome CAS NO 32303-82-5 is a protected dipeptide derivative, specifically the methyl ester of the Z-protected form of alanyl-histidine. This compound is a crucial building block in peptide synthesis, offering controlled reactivity for the sequential assembly of complex peptide chains. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of bioactive peptides, enzyme inhibitors, and novel therapeutic agents.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled incorporation of the Ala-His sequence into longer peptide chains.
• Solution-Phase Peptide Chemistry: Used in classical coupling strategies for constructing specific dipeptide motifs.
• Pharmaceutical Research: Serves as a precursor in the development of peptide-based drugs targeting various physiological pathways.
• Biochemical Tool Development: Employed in the synthesis of substrates or inhibitors for studying protease and metalloenzyme activity.
• Structure-Activity Relationship (SAR) Studies: Facilitates the exploration of histidine-containing peptide regions to optimize biological activity and stability.

Basic Information

Product Name	Z-Ala-His-Ome
CAS No.	32303-82-5
Molecular Formula	C17H22N4O5
Molecular Weight	362.38 g/mol
Synonyms	N-Carbobenzoxy-L-alanyl-L-histidine methyl ester; Z-L-Ala-L-His-OMe; Nα-Benzyloxycarbonyl-L-alanyl-L-histidine methyl ester; CBZ-L-Ala-L-His-OMe; Z-Ala-His-OMe; Z-A-H-Ome; L-Alanyl-L-histidine, N-[(phenylmethoxy)carbonyl]-, methyl ester
EINECS	Contact for details

Quality Control

Our Z-Ala-His-Ome is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification, chiral analysis to confirm enantiomeric integrity, and identity confirmation by spectroscopic methods. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/MS)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.