Description

16,(5Alpha)-Pregnen-3-α-Ol-11,20-Dione CAS NO 32226-03-2 is a high-purity steroid intermediate, specifically a pregnane derivative, critical for advanced pharmaceutical synthesis. This compound serves as a key building block in the production of specialized corticosteroids and other bioactive steroid molecules. It is essential for research and development laboratories, pharmaceutical manufacturers, and fine chemical companies engaged in the synthesis of complex therapeutic agents.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of potent corticosteroids and other steroid-based active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for the discovery and structural modification of new steroid-derived therapeutic compounds.
• Biochemical Research: Serves as a reference standard or starting material for studying steroid metabolism, receptor binding, and enzymatic pathways.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing high-value, low-volume specialty chemicals.

Basic Information

Product Name	16,(5Alpha)-Pregnen-3-α-Ol-11,20-Dione
CAS No.	32226-03-2
Molecular Formula	C21H30O3
Molecular Weight	330.46 g/mol
Synonyms	11,20-Dioxopregn-5-en-3α-ol; 3α-Hydroxy-5-pregnene-11,20-dione; 5-Pregnene-3α-ol-11,20-dione; 16,(5α)-Pregnen-3α-ol-11,20-dione; Pregn-5-ene-3α,11β,20-triol-20-one (related); 11-Ketopregnanolone (related form); Steroid Intermediate 32226-03-2
EINECS	Contact for details

Quality Control

Our 16,(5Alpha)-Pregnen-3-α-Ol-11,20-Dione is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and residual solvent analysis, to ensure it meets exacting standards for pharmaceutical R&D and synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.