Description

(1R,3S)-1,3-Bis(Acetylamino)Cyclohexane CAS NO 32189-20-1 is a high-purity, stereochemically defined chiral intermediate of significant importance in advanced organic synthesis. Its value lies in its rigid cyclohexane backbone and dual protected amino functionality, making it a versatile building block for constructing complex molecular architectures. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting neurological and metabolic disorders.
• Agrochemical Research: Used in the development of advanced, enantiomerically pure pesticides and herbicides with improved efficacy and environmental profiles.
• Ligand and Catalyst Precursor: Serves as a starting material for the preparation of chiral ligands used in asymmetric catalysis.
• Peptidomimetics and Conformationally Restricted Scaffolds: The 1,3-diamino substitution pattern on the cyclohexane ring is valuable for designing and synthesizing peptidomimetic compounds.
• Material Science Research: Potential building block for advanced polymers and specialty materials requiring specific stereochemistry.
• Academic and R&D Laboratories: Employed in fundamental research exploring new synthetic methodologies and structure-activity relationships.

Basic Information

Product Name	(1R,3S)-1,3-Bis(Acetylamino)Cyclohexane
CAS No.	32189-20-1
Molecular Formula	C10H18N2O2
Molecular Weight	198.26 g/mol
Synonyms	(1R,3S)-1,3-Diacetamidocyclohexane; (1R,3S)-N1,N3-Diacetylcyclohexane-1,3-diamine; cis-1,3-Bis(acetylamino)cyclohexane; (1R,3S)-1,3-Bis(acetamido)cyclohexane; 1,3-Cyclohexanediamine, N1,N3-diacetyl-, (1R,3S)-; Chiral 1,3-diacetamidocyclohexane; (1R,3S)-1,3-Diaminocyclohexane diacetamide
EINECS	Contact for details

Quality Control

Our (1R,3S)-1,3-Bis(Acetylamino)Cyclohexane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting R&D and process chemistry standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.