Description

L-Leucine Hydroxamate is a specialized amino acid derivative with the CAS number 31982-78-2, primarily utilized as a biochemical building block and research reagent. This compound is valued for its role in studying enzyme inhibition, particularly as a potential ligand for metalloenzymes, and in the synthesis of more complex bioactive molecules. It serves the critical needs of research institutions, pharmaceutical development labs, and fine chemical manufacturers engaged in proteomics, medicinal chemistry, and advanced material science.

Application

• Biochemical Research: Used as a standard or reagent in enzymatic studies, particularly for investigating hydroxamate-based inhibitors of metalloproteases.
• Pharmaceutical Intermediates: Serves as a key chiral synthon in the research and development of novel therapeutic agents and drug candidates.
• Proteomics & Enzyme Assays: Employed in laboratory settings to study protein-metal interactions and enzyme kinetics.
• Chelating Agent Studies: Investigated for its metal-chelating properties in various chemical and biological systems.
• Academic Research: A valuable tool in university and institutional labs for organic synthesis and medicinal chemistry projects.
• Fine Chemical Synthesis: Used as a building block for the preparation of more complex, high-value specialty chemicals.

Basic Information

Product Name	L-Leucine Hydroxamate
CAS No.	31982-78-2
Molecular Formula	C6H14N2O2
Molecular Weight	146.19 g/mol
Synonyms	L-2-Amino-4-methylpentanoic acid hydroxamate; (S)-2-Amino-4-methylpentanoic acid hydroxamate; Leucinehydroxamic acid; H-Leu-NHOH; (S)-2-Amino-4-methylvaleric acid hydroxamate; L-α-Aminoisocaproic acid hydroxamate
EINECS	Contact for details

Quality Control

Our L-Leucine Hydroxamate is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, chiral purity, and impurity profiles. Our quality system is designed to meet the stringent requirements of research and development sectors.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled under an inert atmosphere when appropriate for long-term storage. Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-Isomer)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.