Description

Pentanamide, 2-Amino-n-Hydroxy-3-Methyl-, (S-(R*,R*))- is a high-purity, stereochemically defined chiral compound, identified by CAS NO 31982-77-1, that serves as a critical building block in advanced organic synthesis. Its value lies in its unique molecular architecture, featuring both amino and hydroxy functional groups on a chiral carbon backbone, making it an essential intermediate for constructing complex, biologically active molecules. This compound is primarily needed by research institutions and pharmaceutical development companies engaged in the creation of novel therapeutics, agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in antibiotic and enzyme inhibitor pathways.
• Agrochemical Synthesis: Used in the production of advanced, stereospecific pesticides and herbicides where specific chirality is crucial for biological activity.
• Biochemical Research: Serves as a precursor or standard in biochemical studies involving peptide mimetics and enzyme-substrate interactions.
• Fine Chemical Manufacturing: Employed in the multi-step synthesis of complex organic molecules for specialty chemical applications.
• Ligand and Catalyst Development: Acts as a starting material for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	Pentanamide, 2-Amino-n-Hydroxy-3-Methyl-, (S-(R*,R*))-
CAS No.	31982-77-1
Molecular Formula	C6H14N2O2
Molecular Weight	146.19 g/mol
Synonyms	(2S,3R)-2-Amino-3-methyl-5-hydroxypentanamide; L-threoninamide derivative; 2-Amino-3-methyl-5-hydroxypentanamide; (S,R)-2-Amino-3-methyl-5-hydroxypentanamide; 5-Hydroxy-L-isoleucinamide; A chiral β-hydroxy γ-amino amide; A building block for statin side chains
EINECS	Contact for details

Quality Control

Our production of Pentanamide, 2-Amino-n-Hydroxy-3-Methyl-, (S-(R*,R*))- adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. The material is characterized and released against comprehensive specifications, including chiral purity and chemical identity. Certificates of Analysis (COA) detailing all critical quality attributes are provided with each shipment to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture uptake and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.