Description

n-(2-Nitrophenyl)-L-Proline is a specialized chiral proline derivative featuring a nitro-substituted aromatic ring. This compound is a valuable synthetic intermediate and building block in advanced organic synthesis and pharmaceutical research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for applications requiring specific stereochemistry and functional group manipulation.

Application

• Pharmaceutical Intermediate: Key chiral building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates.
• Asymmetric Catalysis: Used as a precursor or ligand in the development of chiral catalysts for stereoselective reactions.
• Peptidomimetics Research: Incorporated into peptide analogs and peptidomimetic compounds to modulate biological activity and stability.
• Agrochemical Synthesis: Intermediate in the production of chiral agrochemicals, such as herbicides and fungicides.
• Chemical Biology Probes: Serves as a component in the design of molecular probes for studying enzyme mechanisms and protein interactions.
• Academic & Industrial R&D: Employed in research laboratories for method development and exploring new synthetic pathways.

Basic Information

Product Name	n-(2-Nitrophenyl)-L-Proline
CAS No.	31981-54-1
Molecular Formula	C₁₁H₁₂N₂O₄
Molecular Weight	236.22 g/mol
Synonyms	L-Proline, 1-(2-nitrophenyl)-; 1-(2-Nitrophenyl)-L-proline; (S)-1-(2-Nitrophenyl)pyrrolidine-2-carboxylic acid; (S)-1-(2-Nitrophenyl)-2-pyrrolidinecarboxylic acid; n-(2-Nitrophenyl)-L-proline; 2-Pyrrolidinecarboxylic acid, 1-(2-nitrophenyl)-, (S)-; L-1-(2-Nitrophenyl)proline
EINECS	Contact for details

Quality Control

Our n-(2-Nitrophenyl)-L-Proline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. This product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to light brown powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 98.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.