Description

N5-[(2,4-Dimethoxyphenyl)Methyl]-N2-[(Benzyloxy)Carbonyl]-L-Glutamine Methyl Ester is a sophisticated, protected glutamine derivative that serves as a critical building block in advanced organic synthesis. This compound is engineered to provide selective reactivity, enabling the precise construction of complex peptides and other bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents and biochemical probes.

Application

• Peptide Synthesis: A key protected intermediate for the solid-phase and solution-phase synthesis of complex peptides, particularly those requiring selective side-chain manipulation.
• Pharmaceutical Research: Used in the research and development of new drug candidates, especially in medicinal chemistry programs targeting neurological and metabolic disorders.
• Bioconjugation: Serves as a versatile linker or spacer molecule for attaching peptides to other biomolecules, surfaces, or reporter tags in bioconjugation chemistry.
• Chemical Biology: Employed in the synthesis of activity-based probes and other tools for studying enzyme function and protein-protein interactions.
• Academic Research: A valuable reagent for university and institutional labs exploring new synthetic methodologies and the structure-activity relationships of glutamine-containing compounds.

Basic Information

Product Name	N5-[(2,4-Dimethoxyphenyl)Methyl]-N2-[(Benzyloxy)Carbonyl]-L-Glutamine Methyl Ester
CAS No.	31874-48-3
Molecular Formula	C23H28N2O7
Molecular Weight	444.48 g/mol
Synonyms	Z-Gln(2,4-Dmp)-OMe; Cbz-Gln(2,4-Dmp)-OMe; N2-[(Benzyloxy)carbonyl]-N5-[(2,4-dimethoxyphenyl)methyl]-L-glutamine methyl ester; L-Glutamine, N2-[(benzyloxy)carbonyl]-N5-[(2,4-dimethoxyphenyl)methyl]-, methyl ester; Methyl N2-(benzyloxycarbonyl)-N5-(2,4-dimethoxybenzyl)-L-glutaminate
EINECS	Contact for details

Quality Control

Every batch of N5-[(2,4-Dimethoxyphenyl)Methyl]-N2-[(Benzyloxy)Carbonyl]-L-Glutamine Methyl Ester is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency that meet the exacting standards of pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant and inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.