Description

6-Fluorobenzo[D]Isothiazol-3-Amine is a high-purity fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecules with tailored biological and material properties. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and infectious diseases.
• Agrochemical Research: Serves as a building block for synthesizing novel herbicides, fungicides, and insecticides with potential for improved efficacy and environmental profiles.
• Material Science: Used in the research and development of advanced organic electronic materials, such as OLEDs and semiconductors, due to its electron-deficient isothiazole core.
• Chemical Synthesis: Acts as a versatile precursor for further functionalization, enabling the introduction of the fluorinated benzoisothiazole moiety into more complex molecular architectures.
• Bioconjugation & Probe Development: Utilized in life sciences research for creating fluorescent probes or affinity labels to study biological processes.

Basic Information

Product Name	6-Fluorobenzo[D]Isothiazol-3-Amine
CAS No.	31857-81-5
Molecular Formula	C7H5FN2S
Molecular Weight	168.19 g/mol
Synonyms	3-Amino-6-fluorobenzo[d]isothiazole; 6-Fluorobenzo[d]isothiazol-3-amine; 6-Fluoro-1,2-benzisothiazol-3-amine; 6-Fluoro-3-aminobenzo[d]isothiazole; 6-Fluoro-3-isothiazolamine; 31857-81-5; 6-Fluorobenzoisothiazol-3-ylamine; 6-F-BTA
EINECS	Contact for details

Quality Control

Our 6-Fluorobenzo[D]Isothiazol-3-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.