Description

S-(4-Bromobenzyl)Glutathione is a synthetically modified tripeptide derivative of glutathione, featuring a 4-bromobenzyl group attached to the sulfur atom. This structural modification makes it a valuable biochemical tool and a key intermediate in the study of glutathione S-transferase (GST) enzyme activity and detoxification pathways. It is primarily utilized by researchers and manufacturers in the life sciences and pharmaceutical development sectors. The compound is essential for investigating metabolic processes, developing enzyme inhibitors, and synthesizing more complex bioactive molecules.

Application

• Biochemical Research: Used as a standard, substrate, or inhibitor in enzymatic studies of Glutathione S-Transferases (GSTs).
• Pharmaceutical Intermediates: Serves as a key building block in the synthesis of potential drug candidates targeting oxidative stress and detoxification pathways.
• Metabolite Studies: Employed to investigate and characterize the conjugates formed during Phase II metabolism of xenobiotics.
• Proteomics & Biomarker Discovery: Utilized in affinity chromatography and pull-down assays to isolate and identify GST isoforms and their interacting partners.
• Diagnostic Reagent Development: Acts as a component in the development of assay kits for measuring GST activity in clinical and environmental samples.
• Reference Standard: Provides a high-purity analytical standard for quality control and method validation in analytical laboratories.

Basic Information

Product Name	S-(4-Bromobenzyl)Glutathione
CAS No.	31702-37-1
Molecular Formula	C17H23BrN3O6S
Molecular Weight	477.35 g/mol
Synonyms	4-Bromobenzyl Glutathione; S-(p-Bromobenzyl)glutathione; γ-Glu-Cys(4-Br-Bn)-Gly; L-γ-Glutamyl-S-(4-bromobenzyl)-L-cysteinylglycine; NSC 113928; Glutathione S-(4-bromobenzyl) conjugate; GST Inhibitor (4-Bromobenzyl derivative)
EINECS	Contact for details

Quality Control

Our S-(4-Bromobenzyl)Glutathione is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity. For long-term storage, consider desiccants or storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.