Description

Coenzyme A Disulfide is a critical oxidized form of the essential metabolic cofactor, Coenzyme A (CoA). This compound plays a significant role in cellular redox biochemistry, serving as a key intermediate and regulator in metabolic pathways. It is primarily utilized in biochemical research, pharmaceutical development, and as a reference standard for analytical methods. Professionals in life sciences and fine chemical synthesis rely on its consistent quality for studies in energy metabolism, enzyme kinetics, and antioxidant systems.

Application

• Biochemical Research & Reference Standard: Used as a high-purity standard in HPLC, LC-MS, and enzymatic assays to study CoA-dependent metabolic pathways.
• Pharmaceutical Intermediates: Serves as a key building block in the synthesis of novel therapeutic agents targeting metabolic disorders.
• Enzymology Studies: Essential for investigating the kinetics and mechanisms of enzymes like CoA-disulfide reductase and other redox-regulating proteins.
• Cell Culture & Metabolism: Applied in research to modulate the intracellular redox state and study its impact on cell signaling and viability.
• Diagnostic Reagent Manufacturing: Incorporated into diagnostic kits and reagents for clinical testing related to metabolic function.
• Nutritional & Cosmetic Science: Explored in advanced formulations for its potential role in cellular energy and antioxidant support.

Basic Information

Product Name	Coenzyme A Disulfide
CAS No.	31664-36-5
Molecular Formula	C23H36N7O17P3S2
Molecular Weight	919.63 g/mol
Synonyms	CoA Disulfide; Oxidized Coenzyme A; CoASS-CoA; Diphospho-CoA; Coenzyme A Oxidized Form; 3'-Dephospho-CoA disulfide; Adenosine 3'-diphosphate 5'-diphosphate coupled with pantetheine disulfide
EINECS	Contact for details

Quality Control

Our Coenzyme A Disulfide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and tests for residual solvents and moisture. We provide comprehensive Certificates of Analysis (COA) with each shipment to ensure traceability and compliance with your research or production specifications. Our quality commitment supports applications requiring high-purity biochemicals.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This material is hygroscopic (moisture-sensitive). Allow the sealed container to equilibrate to room temperature before opening to minimize condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.