Description

Formamide, n-[(1R)-1-Phenylethyl]- is a chiral formamide derivative characterized by its (R)-1-phenylethyl substituent. This compound is a valuable chiral building block and intermediate in asymmetric synthesis, offering a handle for stereochemical control in complex molecule construction. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active pharmaceutical ingredients (APIs), chiral ligands, and other fine chemicals.

Application

• Chiral Intermediate in Pharmaceutical Synthesis: A key building block for the preparation of enantiomerically pure APIs, including potential candidates for neurological and cardiovascular therapies.
• Asymmetric Catalyst and Ligand Precursor: Serves as a starting material for synthesizing chiral auxiliaries, ligands for transition metal catalysis, and organocatalysts.
• Agrochemical Research & Development: Used in the synthesis of chiral herbicides, fungicides, and plant growth regulators where specific stereochemistry is crucial for bioactivity.
• Material Science Research: Investigated for the development of chiral polymers, liquid crystals, and functional organic materials with specific optical properties.
• Academic & Industrial R&D: A versatile reagent in methodological development for new asymmetric transformations and C-N bond-forming reactions.

Basic Information

Product Name	Formamide, n-[(1R)-1-Phenylethyl]-
CAS No.	31502-34-8
Molecular Formula	C9H11NO
Molecular Weight	149.19 g/mol
Synonyms	N-[(1R)-1-Phenylethyl]formamide; (R)-N-(1-Phenylethyl)formamide; (R)-N-(α-Methylbenzyl)formamide; (R)-1-Phenylethylformamide; (R)-N-Formyl-α-methylbenzylamine; (R)-N-(1-Phenylethyl)carboxamide; (R)-N-Formyl-1-phenylethylamine; (R)-α-Methylbenzylformamide
EINECS	Contact for details

Quality Control

Our chiral intermediates are produced under strict quality management systems. Each batch of Formamide, n-[(1R)-1-Phenylethyl]- is subjected to rigorous analytical testing, including chiral HPLC to confirm high enantiomeric excess (ee) and identity verification. We provide comprehensive Certificates of Analysis (COA) detailing purity, chiral purity, and impurity profiles to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.