Description

3β-(Acetyloxy)-5β-Bufa-14,16,20,22-Tetrenolide CAS NO 31444-09-4 is a specialized bufadienolide derivative, a class of steroid-like compounds with significant biological activity. This high-purity intermediate is critical for pharmaceutical research and development, particularly in the study of cardiac glycosides and novel therapeutic agents. It serves as a key building block for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors requiring precise and reliable synthetic components.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel bufadienolide-based drug candidates and active pharmaceutical ingredients (APIs).
• Cardiovascular Research: Used in biochemical and pharmacological studies to investigate mechanisms related to sodium-potassium ATPase inhibition and cardiac activity.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method development in HPLC and LC-MS assays.
• Medicinal Chemistry: Provides a scaffold for structural modification and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Biochemical Tool Compound: Utilized in in vitro and ex vivo studies to probe specific biological pathways and protein interactions.

Basic Information

Product Name	3β-(Acetyloxy)-5β-Bufa-14,16,20,22-Tetrenolide
CAS No.	31444-09-4
Molecular Formula	C₂₆H₃₄O₅
Molecular Weight	426.55 g/mol
Synonyms	3β-Acetoxy-14,15β-epoxy-5β-bufa-16,20,22-trienolide; 3β-Acetoxy-5β-bufa-14,16,20,22-tetraenolide; Bufadienolide acetate derivative; 14,15β-Epoxy-3β-hydroxy-5β-bufa-16,20,22-trienolide 3-acetate; 3β-Acetyloxy-5β-bufa-14,16,20,22-tetraenolide; 3β-Acetoxy-5β,14β-bufa-16,20,22-trienolide
EINECS	Contact for details

Quality Control

Our 3β-(Acetyloxy)-5β-Bufa-14,16,20,22-Tetrenolide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS). We provide Certificates of Analysis (COA) with detailed specifications to ensure traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, cool, and well-ventilated area. Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.