Description

4-Fluoro-2-Hydroxyphenylacetic Acid is a versatile fluorinated aromatic building block with a carboxylic acid and a phenolic hydroxyl group. This compound is valued for its role as a key intermediate in the synthesis of complex molecules, particularly in the pharmaceutical sector. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced material industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of non-steroidal anti-inflammatory drugs (NSAIDs) and other active pharmaceutical ingredients (APIs) containing a fluorinated aromatic core.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the fluorine atom can enhance biological activity and stability.
• Liquid Crystal & OLED Material Research: Serves as a building block for fluorinated organic molecules used in electronic displays and optoelectronic devices.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new organic reactions and creating novel chemical entities.
• Fine Chemical Production: Acts as a specialized intermediate for manufacturing dyes, pigments, and other performance chemicals.

Basic Information

Product Name	4-Fluoro-2-Hydroxyphenylacetic Acid
CAS No.	31338-67-7
Molecular Formula	C8H7FO3
Molecular Weight	170.14 g/mol
Synonyms	2-(4-Fluoro-2-hydroxyphenyl)acetic acid; (4-Fluoro-2-hydroxyphenyl)acetic acid; 4-Fluoro-2-hydroxybenzeneacetic acid; 2-Hydroxy-4-fluorophenylacetic acid; 4-Fluoro-2-hydroxy-α-toluic acid; 4-Fluoro-2-hydroxybenzylformic acid; 4-Fluoro-2-hydroxyphenyl ethanoic acid
EINECS	Contact for details

Quality Control

Our 4-Fluoro-2-Hydroxyphenylacetic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Custom synthesis and purity grades (e.g., >98%, >99%) are available to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The compound is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	158 - 162 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.