Description

1,4,5,6-Tetrahydronicotinamide Adenine Dinucleotide is a chemically reduced form of the essential coenzyme NAD, offering unique biochemical properties for research and industrial biocatalysis. This compound is critical for applications requiring a stable, reduced nicotinamide cofactor to drive enzymatic reactions in synthetic pathways. It is primarily utilized by researchers and process developers in the pharmaceutical, biotechnology, and fine chemical synthesis industries.

Application

• Enzymatic Synthesis & Biocatalysis: Acts as a cofactor for oxidoreductase enzymes in the production of chiral intermediates for active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a substrate or cofactor in metabolic pathway studies, enzyme kinetics, and mechanism of action research.
• Diagnostic Reagent Manufacturing: Serves as a key component in the formulation of diagnostic kits and assay systems for clinical and research laboratories.
• Cosmeceutical & Nutraceutical Development: Investigated for its role in cellular energy metabolism and redox balance in advanced skincare and wellness products.
• Industrial Enzyme Systems: Employed in immobilized enzyme reactors for the sustainable production of fine chemicals and flavors.

Basic Information

Product Name	1,4,5,6-Tetrahydronicotinamide Adenine Dinucleotide
CAS No.	31172-31-3
Molecular Formula	C21H29N7O14P2
Molecular Weight	665.44 g/mol
Synonyms	1,4,5,6-Tetrahydro-NAD; TH-NAD; Tetrahydronicotinamide-adenine dinucleotide; Reduced NAD analog; Dihydronicotinamide adenine dinucleotide (fully reduced form); 1,4,5,6-Tetrahydro-NAD+; Nicotinamide adenine dinucleotide, 1,4,5,6-tetrahydro-
EINECS	Contact for details

Quality Control

Our 1,4,5,6-Tetrahydronicotinamide Adenine Dinucleotide is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR for structural confirmation, and tests for residual solvents and moisture to ensure it meets the high standards required for research and process applications. Certificates of Analysis (COA) with lot-specific data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the sealed container to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.