Description

n-Acetyl-3-Methylene-4-(1H,1H-Nonafluoropentyl)Pyrrolidine is a specialized fluorinated pyrrolidine derivative, a high-value building block in advanced organic synthesis. Its core value lies in the unique combination of a reactive pyrrolidine scaffold and a perfluorinated alkyl chain, which imparts significant lipophilicity and metabolic stability to target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients, particularly for applications requiring enhanced bioavailability and target binding affinity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, including protease inhibitors, receptor antagonists, and other bioactive molecules where the fluorine moiety improves pharmacokinetic properties.
• Agrochemical Research: Used in developing advanced pesticides and herbicides, where the fluorinated side chain can enhance penetration, stability, and activity.
• Material Science: Serves as a monomer or modifier in creating specialty polymers with unique surface properties, such as oil- and water-repellency (fluorosurfactants/coatings).
• Ligand & Catalyst Development: Employed in organometallic chemistry to create novel fluorinated ligands for catalysis, potentially influencing selectivity and reaction efficiency.
• Diagnostic Agent Synthesis: A building block for fluorinated probes and contrast agents used in imaging technologies like PET (Positron Emission Tomography) or MRI.

Basic Information

Product Name	n-Acetyl-3-Methylene-4-(1H,1H-Nonafluoropentyl)Pyrrolidine
CAS No.	31164-13-3
Molecular Formula	C12H12F9NO
Molecular Weight	357.22 g/mol
Synonyms	1-[3-Methylene-4-(1H,1H-nonafluoropentyl)pyrrolidin-1-yl]ethanone; 1-Acetyl-3-methylene-4-(1H,1H-nonafluoropentyl)pyrrolidine; 4-(1H,1H-Nonafluoropentyl)-3-methylenepyrrolidine-1-acetic Acid Methyl Ester (common misnomer); N-Acetyl-3-methylene-4-(nonafluoropentyl)pyrrolidine; Fluorinated Pyrrolidine Acetamide Derivative; 31164-13-3; 3-Methylene-4-(perfluoropentyl)pyrrolidine-1-acetamide
EINECS	Contact for details

Quality Control

Our n-Acetyl-3-Methylene-4-(1H,1H-Nonafluoropentyl)Pyrrolidine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures the material meets the stringent requirements for research and cGMP-grade pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Standard Grade)
Purity (GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.