Description

(2S)-2-Amino-3-[3,5-Diiodo-4-(3-Iodo-4-Sulfooxy-Phenoxy)Phenyl]Propanoic Acid is a complex, multi-iodinated aromatic amino acid derivative of significant interest in advanced research and development. This compound matters for its unique structural features, including a sulfated phenolic ether linkage, which make it a valuable synthetic intermediate and a potential candidate for creating specialized biochemical probes. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers focused on developing novel thyroid hormone analogs, enzyme inhibitors, or radiolabeling precursors for diagnostic applications.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel thyroid hormone receptor ligands and analogs.
• Biochemical Research: Used in the development of enzyme inhibitors and receptor-binding studies due to its iodinated phenolic structure.
• Diagnostic Agent Precursor: Acts as a precursor molecule for potential radiopharmaceuticals or contrast agents, leveraging its high iodine content.
• Fine Chemical Synthesis: Employed in specialized organic synthesis routes to create complex, iodinated aromatic compounds for material science or agrochemical research.
• Reference Standard: Utilized as a high-purity analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	(2S)-2-Amino-3-[3,5-Diiodo-4-(3-Iodo-4-Sulfooxy-Phenoxy)Phenyl]Propanoic Acid
CAS No.	31135-55-4
Molecular Formula	C15H12I3NO6S
Molecular Weight	746.94 g/mol
Synonyms	L-Thyronine, O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-, 4'-sulfate; 3,5,3'-Triiodothyronine 4'-sulfate; T3 Sulfate; TRIAC Sulfate; (2S)-2-Amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoic acid 4'-sulfate; 31135-55-4; Reverse T3 Sulfate
EINECS	Contact for details

Quality Control

Our production of (2S)-2-Amino-3-[3,5-Diiodo-4-(3-Iodo-4-Sulfooxy-Phenoxy)Phenyl]Propanoic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical characterization using techniques such as HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific research or cGMP guidelines upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a desiccated environment to prevent degradation. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.