Description

3-Acetamido-5-(Acetyl-Methyl-Amino)-2,4,6-Triiodo-n-[(2S,3R,4S,5R)-1,3,4,5,6-Pentahydroxyhexan-2-Yl]Benzamide is a specialized, high-purity iodinated organic compound primarily used as a key intermediate in the synthesis of advanced X-ray contrast media. Its complex molecular structure, featuring a triiodinated benzene ring linked to a sugar derivative, is engineered for optimal radiopacity and biological compatibility. This compound is essential for pharmaceutical R&D and manufacturing teams focused on developing next-generation non-ionic, low-osmolar contrast agents for diagnostic imaging.

Application

• Pharmaceutical Intermediate: Primary building block for synthesizing iopamidol, iohexol, and other non-ionic iodinated contrast agents.
• Contrast Media Research: Critical raw material in R&D for novel X-ray and CT (Computed Tomography) imaging agents with improved safety profiles.
• Diagnostic Agent Manufacturing: Used in GMP production processes for final drug substances intended for intravascular, intrathecal, and body cavity administration.
• Chemical Reference Standard: Serves as a high-purity standard for analytical method development and quality control in pharmaceutical labs.
• Radiopharmaceutical Precursor: Potential intermediate in the development of targeted imaging agents.

Basic Information

Item	Detail
Product Name	3-Acetamido-5-(Acetyl-Methyl-Amino)-2,4,6-Triiodo-n-[(2S,3R,4S,5R)-1,3,4,5,6-Pentahydroxyhexan-2-Yl]Benzamide
CAS No.	31112-66-0
Molecular Formula	C18H22I3N3O8
Molecular Weight	833.09 g/mol
Synonyms	5-Acetamido-N,2-bis(acetyl-methyl-amino)-2,4,6-triiodo-N-[(2S,3R,4S,5R,6R)-1,3,4,5,6-pentahydroxyhexan-2-yl]isophthalamide; Iopamidol Impurity; Iopamidol Intermediate; Iohexol Related Compound; 1-Deoxy-1-(methylamino)-D-glucitol, N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-5-[(methylamino)carbonyl]-N-(2-hydroxyethyl)isophthalamide derivative; Non-Ionic Contrast Media Intermediate; Triiodinated Benzamide Derivative
EINECS	Contact for details

Quality Control

Our 3-Acetamido-5-(Acetyl-Methyl-Amino)-2,4,6-Triiodo-n-[(2S,3R,4S,5R)-1,3,4,5,6-Pentahydroxyhexan-2-Yl]Benzamide is manufactured under strict quality systems suitable for pharmaceutical applications. Each batch undergoes rigorous analytical testing, including HPLC for purity and related substances, to ensure compliance with stringent internal specifications. A comprehensive Certificate of Analysis (COA) detailing identity, assay, impurity profile, and residual solvents is provided with every shipment to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.