Description

Coproporphyrinogen I CAS NO 31110-56-2 is a key biochemical intermediate in the porphyrin biosynthesis pathway, specifically in the formation of heme and chlorophyll. Its primary commercial and research value lies in its role as a critical standard and reference material for analytical studies in biochemistry and clinical diagnostics. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic reagent industries, particularly for investigating porphyrias and other metabolic disorders related to heme synthesis.

Application

• Biochemical Research Standard: Serves as a high-purity reference standard in enzymatic studies of the heme biosynthesis pathway.
• Clinical Diagnostics: Used in the development and calibration of diagnostic assays for congenital erythropoietic porphyria and other porphyrin-related disorders.
• Pharmaceutical Development: Acts as a critical intermediate in research focused on modulating heme production for therapeutic applications.
• Metabolite Analysis: Employed as an analytical standard in HPLC and LC-MS methods for quantifying porphyrinogen levels in biological samples.
• Enzyme Activity Assays: Utilized as a specific substrate for measuring the activity of coproporphyrinogen oxidase in vitro.
• Educational & Reference Material: Supplied to academic and institutional laboratories for teaching and advanced research in bioinorganic chemistry.

Basic Information

Product Name	Coproporphyrinogen I
CAS No.	31110-56-2
Molecular Formula	C₃₆H₄₄N₄O₈
Molecular Weight	648.76 g/mol
Synonyms	Coproporphyrinogen I; 3,8,13,18-Tetramethyl-21H,23H-porphine-2,7,12,17-tetrapropanoic acid (reduced form); Coprogen I; Coproporphyrinogen III isomer I; 2,7,12,17-Tetrakis(2-carboxyethyl)-3,8,13,18-tetramethylporphyrinogen; Porphyrinogen I
EINECS	Contact for details

Quality Control

Our Coproporphyrinogen I is produced and handled under strict quality protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive research and diagnostic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profiles. We adhere to relevant industry standards for biochemical reagents, ensuring material integrity for your critical work.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. Due to its hygroscopic and light-sensitive nature, the material should be handled in a controlled environment to minimize exposure to moisture and ambient light. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	Off-white to light tan powder
Identification (HPLC)	Conforms to reference standard
Identification (UV-Vis)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Solubility	Soluble in alkaline aqueous solutions, DMSO
Loss on Drying	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.