Description

Polyinosinic Acid CAS NO 30918-54-8 is a synthetic, high molecular weight polynucleotide composed of inosine monophosphate units. This compound is a critical research-grade biochemical with significant immunostimulatory and antiviral properties. It serves as a vital tool for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly in the development of novel therapeutic agents and vaccine adjuvants.

Application

• Immunological Research: Used as a synthetic analog of double-stranded RNA to study and stimulate innate immune responses, including interferon induction.
• Vaccine Adjuvant Development: Investigated as a potent adjuvant to enhance the efficacy of vaccines by activating pattern recognition receptors like TLR3.
• Antiviral Agent Research: Serves as a model compound for studying broad-spectrum antiviral activity and mechanisms of action against RNA viruses.
• Cell Culture & In Vitro Studies: Employed in cell-based assays to mimic viral infection and probe intracellular signaling pathways.
• Biochemical Standard: Acts as a reference standard in analytical laboratories for quality control of related polynucleotides.
• Drug Delivery & Nanomedicine: Explored as a component in complex formulations for targeted delivery of nucleic acid-based therapeutics.

Basic Information

Product Name	Polyinosinic Acid
CAS No.	30918-54-8
Molecular Formula	(C10H12N4O8P)n
Molecular Weight	Variable (High Polymer)
Synonyms	Poly(I); Polyinosinic-polycytidylic acid homopolymer strand; Inosinic acid homopolymer; 1H-Purine-6-ol, 9-β-D-ribofuranosyl-, homopolymer; Poly I; Poly rI; Polynosinic acid; Poly(inosinic acid)
EINECS	Contact for details

Quality Control

Our Polyinosinic Acid is produced under stringent conditions to ensure batch-to-batch consistency and high purity suitable for research applications. Quality is verified through a comprehensive suite of analytical techniques. Certificates of Analysis (COA) detailing purity, identity, and bioburden are available upon request for every lot.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder or solid
Identification (UV-Vis)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 95% (Poly I content)
Absorbance Ratio (A250/A260)	0.80 - 0.90
Hypochromicity	≥ 25%
Endotoxin Level (LAL)	< 10 EU/mg
Solubility	Soluble in aqueous buffers or sterile water for injection

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.