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2(1H)-Pyrimidinone,4-Amino-1-B-D-Arabinofuranosyl-, 3-Oxide CAS NO 30902-36-4


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CAS No.:30902-36-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2(1H)-Pyrimidinone,4-Amino-1-B-D-Arabinofuranosyl-, 3-Oxide is a nucleoside analogue with a modified pyrimidine base, distinguished by its 3-oxide functional group. This compound is of significant interest in pharmaceutical research and development due to its potential as a key intermediate or active pharmaceutical ingredient (API) in antiviral and anticancer therapies. It is primarily required by research institutions, pharmaceutical manufacturers, and fine chemical suppliers engaged in the synthesis of novel therapeutic agents.

Application

  • Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel antiviral and anticancer nucleoside analogues.
  • Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to understand nucleoside metabolism and related biological pathways.
  • Antiviral Drug Development: Investigated for its potential activity against DNA and RNA viruses due to its structural similarity to natural nucleosides.
  • Oncology Research: Explored for its cytotoxic properties and potential to interfere with cancer cell DNA/RNA synthesis.
  • Reference Standard: Employed as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
  • Process Chemistry: Utilized in scaling up synthetic routes for the production of more complex therapeutic molecules.

Basic Information

Product Name 2(1H)-Pyrimidinone,4-Amino-1-B-D-Arabinofuranosyl-, 3-Oxide
CAS No. 30902-36-4
Molecular Formula C9H13N3O6
Molecular Weight 259.22 g/mol
Synonyms 4-Amino-1-β-D-arabinofuranosyl-2(1H)-pyrimidinone 3-Oxide; 1-β-D-Arabinofuranosyl-4-amino-2(1H)-pyrimidinone 3-Oxide; 4-Amino-1-(β-D-arabinofuranosyl)-2(1H)-pyrimidinone 3-Oxide; Arabinofuranosyl-4-aminopyrimidinone N-oxide; 4-Amino-araU 3-Oxide; 4-Amino-1-β-D-arabinofuranosyl-2-pyrimidinone 3-oxide; 4-Amino-araUridine 3-Oxide
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Quality Control

Our 2(1H)-Pyrimidinone,4-Amino-1-B-D-Arabinofuranosyl-, 3-Oxide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Assay (HPLC) ≥ 98.0%
Water Content (KF) ≤ 2.0%
Residue on Ignition ≤ 0.5%
Heavy Metals ≤ 20 ppm
Related Substances (HPLC) Total impurities ≤ 2.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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