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2(1H)-Pyrimidinone,4-Amino-1-B-D-Arabinofuranosyl-, 3-Oxide CAS NO 30902-36-4
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CAS No.:30902-36-4
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
2(1H)-Pyrimidinone,4-Amino-1-B-D-Arabinofuranosyl-, 3-Oxide is a nucleoside analogue with a modified pyrimidine base, distinguished by its 3-oxide functional group. This compound is of significant interest in pharmaceutical research and development due to its potential as a key intermediate or active pharmaceutical ingredient (API) in antiviral and anticancer therapies. It is primarily required by research institutions, pharmaceutical manufacturers, and fine chemical suppliers engaged in the synthesis of novel therapeutic agents.
Application
- Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel antiviral and anticancer nucleoside analogues.
- Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to understand nucleoside metabolism and related biological pathways.
- Antiviral Drug Development: Investigated for its potential activity against DNA and RNA viruses due to its structural similarity to natural nucleosides.
- Oncology Research: Explored for its cytotoxic properties and potential to interfere with cancer cell DNA/RNA synthesis.
- Reference Standard: Employed as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
- Process Chemistry: Utilized in scaling up synthetic routes for the production of more complex therapeutic molecules.
Basic Information
| Product Name | 2(1H)-Pyrimidinone,4-Amino-1-B-D-Arabinofuranosyl-, 3-Oxide |
| CAS No. | 30902-36-4 |
| Molecular Formula | C9H13N3O6 |
| Molecular Weight | 259.22 g/mol |
| Synonyms | 4-Amino-1-β-D-arabinofuranosyl-2(1H)-pyrimidinone 3-Oxide; 1-β-D-Arabinofuranosyl-4-amino-2(1H)-pyrimidinone 3-Oxide; 4-Amino-1-(β-D-arabinofuranosyl)-2(1H)-pyrimidinone 3-Oxide; Arabinofuranosyl-4-aminopyrimidinone N-oxide; 4-Amino-araU 3-Oxide; 4-Amino-1-β-D-arabinofuranosyl-2-pyrimidinone 3-oxide; 4-Amino-araUridine 3-Oxide |
| EINECS | Contact for details |
Quality Control
Our 2(1H)-Pyrimidinone,4-Amino-1-B-D-Arabinofuranosyl-, 3-Oxide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) with detailed specifications are available upon request.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (IR) | Conforms to structure |
| Identification (HPLC) | Retention time matches reference standard |
| Assay (HPLC) | ≥ 98.0% |
| Water Content (KF) | ≤ 2.0% |
| Residue on Ignition | ≤ 0.5% |
| Heavy Metals | ≤ 20 ppm |
| Related Substances (HPLC) | Total impurities ≤ 2.0% Any single impurity ≤ 1.0% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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