Description

Adenosine N1-Oxide is a chemically modified derivative of the fundamental nucleoside adenosine, characterized by the oxidation of the N1 nitrogen of its purine base. This specific modification is of significant interest in biochemical and pharmaceutical research, serving as a valuable reference standard and synthetic intermediate. It is primarily utilized by researchers and manufacturers in the life sciences sector for investigating nucleoside metabolism, enzyme interactions, and as a precursor in the synthesis of more complex bioactive molecules. The compound is supplied with a high level of purity to ensure reliable and reproducible experimental results.

Application

• Biochemical Research Standard: Used as a high-purity reference material in analytical laboratories for method development and validation in nucleoside analysis.
• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel nucleoside analogs with potential therapeutic applications.
• Enzymology Studies: Employed as a substrate or inhibitor in studies of adenosine deaminase and other nucleoside-modifying enzymes to understand reaction mechanisms.
• Metabolic Pathway Investigation: A tool compound for researching oxidative pathways of adenosine and its role in cellular signaling and energy metabolism.
• Academic Research: Utilized in university and institutional labs for fundamental research in medicinal chemistry and molecular biology.

Basic Information

Product Name	Adenosine N1-Oxide
CAS No.	146-92-9
Molecular Formula	C10H13N5O5
Molecular Weight	283.24 g/mol
Synonyms	1-Oxoadenosine; Adenosine 1-Oxide; 9-β-D-Ribofuranosyladenine 1-Oxide; N1-Oxoadenosine; 6-Amino-9-β-D-ribofuranosyl-9H-purine 1-oxide; Adenosine 1-N-oxide
EINECS	205-690-7

Quality Control

Our Adenosine N1-Oxide is manufactured under controlled conditions and subjected to rigorous analytical testing to ensure it meets the high standards required for research applications. Each batch is characterized using techniques including HPLC, NMR, and mass spectrometry to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.