Description

2-Ethynyl-3-Methylpyridine is a specialized heterocyclic building block featuring both a pyridine ring and a terminal alkyne functional group. This unique molecular structure makes it a versatile intermediate for synthesizing more complex molecules through reactions like Sonogashira coupling and click chemistry. It is primarily required by pharmaceutical research and agrochemical development sectors for creating novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in creating novel pesticides and herbicides with targeted modes of action.
• Ligand and Catalyst Development: Serves as a precursor for constructing sophisticated ligands in transition metal catalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic electronic materials.
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological pathways and protein interactions.
• Academic & R&D: A valuable reagent for methodological studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	2-Ethynyl-3-Methylpyridine
CAS No.	30413-59-3
Molecular Formula	C8H7N
Molecular Weight	117.15 g/mol
Synonyms	3-Methyl-2-ethynylpyridine; 2-Ethynyl-3-picoline; 2-(Ethynyl)-3-methylpyridine; 3-Methyl-2-pyridylethyne; Pyridine, 2-ethynyl-3-methyl-; 2-Ethynyl-3-methylpyridine (principal name)
EINECS	Contact for details

Quality Control

Our 2-Ethynyl-3-Methylpyridine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chromatography and spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.