Description

3-Ethynyl-2-Methylpyridine is a versatile pyridine derivative characterized by its reactive ethynyl and methyl substituents. This compound is a valuable specialty chemical intermediate for advanced synthesis, particularly in the development of complex molecular architectures. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its pyridine core for bioactivity.
• Ligand and Catalyst Precursor: Serves as a starting material for creating specialized ligands in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic materials for electronic or optical applications.
• Chemical Biology Probes: Useful for creating tagged molecules or probes due to the reactivity of the alkyne group in click chemistry reactions.
• Fine Chemical Manufacturing: Intermediate in multi-step custom synthesis for high-value, low-volume specialty chemicals.

Basic Information

Product Name	3-Ethynyl-2-Methylpyridine
CAS No.	30413-55-9
Molecular Formula	C8H7N
Molecular Weight	117.15 g/mol
Synonyms	2-Methyl-3-ethynylpyridine; 3-Ethynyl-2-picoline; 2-Picoline, 3-ethynyl-; 2-Methyl-3-pyridylacetylene; 3-(2-Methylpyridin-3-yl)acetylene; Pyridine, 3-ethynyl-2-methyl-; 3-Ethynyl-2-methylpyridine
EINECS	Contact for details

Quality Control

Our 3-Ethynyl-2-Methylpyridine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and GC-MS and NMR for identity confirmation, to ensure it meets the high standards required for research and process chemistry. A detailed Certificate of Analysis (COA) is provided with every shipment, and custom purity grades are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its easily oxidized nature, minimize headspace and exposure to air after opening.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.