Description

4-(8-Chloro-10,11-Dihydrodibenzo(B,F)Thiepin-10-Yl)-1-Piperazinebutano L Dimaleate is a high-purity pharmaceutical intermediate and active ingredient. This compound is critical for ensuring the quality and efficacy of final drug formulations in the research and development pipeline. It is primarily required by pharmaceutical manufacturers and advanced research institutions for the synthesis of neuropsychiatric and psychotropic therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs) for central nervous system (CNS) drugs.
• Research & Development: Used in preclinical and clinical research for developing new therapeutic agents targeting specific neurological pathways.
• Reference Standard: Serves as a certified reference material (CRM) for quality control and analytical method development in pharmaceutical laboratories.
• Bulk API Manufacturing: Employed in the scaled-up production of finished dosage forms under current Good Manufacturing Practices (cGMP).
• Metabolite Studies: Utilized in pharmacological and toxicological studies to understand drug metabolism and pharmacokinetics.

Basic Information

Product Name	4-(8-Chloro-10,11-Dihydrodibenzo(B,F)Thiepin-10-Yl)-1-Piperazinebutano L Dimaleate
CAS No.	30319-66-5
Molecular Formula	C27H30ClN3O4S
Molecular Weight	528.06 g/mol
Synonyms	Zotepine Dimaleate; Zotepine Dimaleate Salt; 4-(8-Chloro-10,11-dihydrodibenzo[b,f]thiepin-10-yl)-1-piperazinebutanoic Acid Dimaleate; FR-1314; Lodopin; Nipolept; Zotepine Maleate; 2-(4-(8-Chloro-10,11-dihydrodibenzo[b,f]thiepin-10-yl)piperazin-1-yl)ethyl 3,4-dihydroxybut-2-enedioate
EINECS	Contact for details

Quality Control

Our 4-(8-Chloro-10,11-Dihydrodibenzo(B,F)Thiepin-10-Yl)-1-Piperazinebutano L Dimaleate is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single unknown impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.