Description

Poly(Ethylene Oxide)-Block-Polycaprolactone is a well-defined, amphiphilic diblock copolymer synthesized from ethylene oxide and ε-caprolactone monomers. This material is engineered to provide precise control over micelle formation, drug encapsulation, and biodegradation rates, making it a critical component in advanced formulations. It is essential for researchers and manufacturers in the pharmaceutical, biomedical, and specialty materials sectors who require tunable polymer properties for sophisticated applications.

Application

• Drug Delivery Systems: As a key excipient for constructing polymeric micelles and nanoparticles for the controlled release of hydrophobic active pharmaceutical ingredients (APIs).
• Biomedical Engineering: Used in the fabrication of biodegradable scaffolds for tissue engineering and regenerative medicine.
• Advanced Material Science: Serves as a compatibilizer or modifier to enhance the properties of polymer blends and composites.
• Cosmetic Formulations: Employed in high-performance skincare products for its ability to stabilize and deliver active ingredients.
• Hydrogel Formation: Acts as a building block for creating smart, stimuli-responsive hydrogels for various biotechnological applications.
• Surface Modification: Used to create stealth coatings on surfaces or particles to improve biocompatibility and reduce immunogenic response.

Basic Information

Product Name	Poly(Ethylene Oxide)-Block-Polycaprolactone
CAS No.	30174-06-2
Molecular Formula	(C2H4O)m-(C6H10O2)n
Molecular Weight	Variable (dependent on block lengths m and n)
Synonyms	PEO-b-PCL; Poly(ethylene glycol)-block-poly(ε-caprolactone); PEG-PCL Diblock Copolymer; Poly(oxyethylene)-block-poly(caprolactone); Ethylene Oxide/Caprolactone Block Copolymer; Amphiphilic PEO-PCL Diblock; Poly(ethylene oxide)-b-poly(ε-caprolactone); PEG-b-PCL
EINECS	Contact for details

Quality Control

Our Poly(Ethylene Oxide)-Block-Polycaprolactone is produced under stringent quality management systems. Each batch is characterized using advanced analytical techniques including Gel Permeation Chromatography (GPC) and Nuclear Magnetic Resonance (NMR) to confirm molecular weight, block ratio, and purity. Certificates of Analysis (COA) detailing these specifications are provided with every shipment to ensure traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the sealed container to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (IR)	Conforms to structure
Molecular Weight (GPC)	As per customer grade (e.g., 2000-b-2000 Da)
Dispersity (Đ)	≤ 1.2
PEO:PCL Block Ratio (NMR)	As per customer grade (e.g., 50:50)
Residual Monomer (HPLC)	≤ 0.5%
Water Content (KF)	≤ 1.0%
Melting Point (DSC)	Reported value

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.