Description

2-Chloro-10-[3-(Dimethylamino)Propyl]-10H-Phenothiazin-1-Ol is a high-purity phenothiazine derivative, a key advanced pharmaceutical intermediate. This compound matters for its role in the synthesis of specialized active pharmaceutical ingredients (APIs) and for research into novel therapeutic agents. It is primarily needed by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions focused on medicinal chemistry and pharmacology.

Application

• Pharmaceutical Intermediate: Critical building block in the synthesis of phenothiazine-based active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a core scaffold for developing new drug candidates with potential neurological or psychiatric activity.
• Reference Standard: Serves as an analytical standard for quality control and method development in pharmaceutical analysis.
• Chemical Synthesis: Intermediate for the preparation of more complex phenothiazine derivatives for various research applications.
• Biochemical Research: Potential tool compound for studying receptor interactions and biochemical pathways in vitro.

Basic Information

Product Name	2-Chloro-10-[3-(Dimethylamino)Propyl]-10H-Phenothiazin-1-Ol
CAS No.	3926-66-7
Molecular Formula	C₁₇H₁₉ClN₂OS
Molecular Weight	334.86 g/mol
Synonyms	1-Hydroxy-2-chloro-10-(3-dimethylaminopropyl)phenothiazine; 2-Chloro-10-(3-dimethylaminopropyl)phenothiazin-1-ol; 2-Chloro-10H-phenothiazin-1-ol, 10-[3-(dimethylamino)propyl]-; 3926-66-7; 10-(3-Dimethylaminopropyl)-2-chloro-10H-phenothiazin-1-ol; 2-Chloro-10-(3-dimethylaminopropyl)-10H-phenothiazin-1-ol
EINECS	Contact for details

Quality Control

Our 2-Chloro-10-[3-(Dimethylamino)Propyl]-10H-Phenothiazin-1-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep container tightly sealed when not in use to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.