Description

Benzonitrile, 3-Amino-5-Chloro-4-Hydroxy- is a high-purity, multi-functional aromatic nitrile derivative that serves as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring amino, chloro, and hydroxy substituents, provides versatile reactivity for constructing complex heterocyclic and pharmaceutical intermediates. This compound is essential for R&D and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for antimicrobial, anti-inflammatory, and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and plant growth regulators, leveraging its halogen and amino groups for bioactivity.
• Dye and Pigment Manufacturing: Serves as a core structure for producing azo dyes and other high-performance colorants with enhanced lightfastness and thermal stability.
• Ligand and Catalyst Development: Utilized in coordination chemistry to create specialized ligands for catalytic systems and metal-organic frameworks (MOFs).
• Polymer Modification: Acts as a functional monomer or cross-linking agent to introduce specific chemical properties into specialty polymers and resins.
• Research & Development: Employed in academic and industrial labs for methodological studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	Benzonitrile, 3-Amino-5-Chloro-4-Hydroxy-
CAS No.	3861-33-4
Molecular Formula	C7H5ClN2O
Molecular Weight	168.58 g/mol
Synonyms	3-Amino-5-chloro-4-hydroxybenzonitrile; 5-Chloro-4-hydroxy-3-aminobenzonitrile; 2-Amino-6-chloro-3-cyanophenol; 3-Cyano-4,6-diamino-2-chlorophenol (tautomer); 4-Hydroxy-3-amino-5-chlorobenzonitrile; 5-Chloro-3-cyano-4-aminophenol; 2-Chloro-5-cyano-6-aminophenol; ACHB (abbreviation)
EINECS	223-389-9

Quality Control

Every batch of 3-Amino-5-Chloro-4-Hydroxybenzonitrile is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) for each shipment, confirming compliance with customer specifications and relevant industry standards. Our quality commitment supports applications in regulated environments, including cGMP for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound may be light-sensitive and hygroscopic; ensure containers are sealed under an inert atmosphere if specified for high-purity grades.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.