Description

2'-(Trifluoromethoxy)Acetanilide is a high-purity, specialized organic intermediate featuring a trifluoromethoxy aniline core. This compound is valued for its role in introducing the metabolically stable and lipophilic trifluoromethoxy group into target molecules, which is a critical modification in advanced pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in developing candidates for central nervous system (CNS) and anti-inflammatory therapies.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethoxy group enhances biological activity and environmental stability.
• Material Science Research: Serves as a precursor for developing specialty polymers, liquid crystals, and organic electronic materials requiring specific fluorine-based functionalities.
• Chemical Biology & Proteomics: Employed as a reagent or scaffold in the design of molecular probes and enzyme inhibitors for biochemical research.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2'-(Trifluoromethoxy)Acetanilide
CAS No.	3832-55-1
Molecular Formula	C9H8F3NO2
Molecular Weight	219.16 g/mol
Synonyms	N-(2-(Trifluoromethoxy)phenyl)acetamide; 2-Acetamidophenyl trifluoromethyl ether; 2'-Trifluoromethoxyacetanilide; 1-Acetyl-2-(trifluoromethoxy)aniline; Acetamide, N-[2-(trifluoromethoxy)phenyl]-; o-(Trifluoromethoxy)acetanilide; 2-(Trifluoromethoxy)acetamilide
EINECS	223-336-6

Quality Control

Our 2'-(Trifluoromethoxy)Acetanilide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.