Description

Benzene, 2-Fluoro-4-Iodo-1-Methoxy- is a halogenated aromatic building block of significant interest in advanced organic synthesis. This compound matters because its unique substitution pattern, featuring both fluorine and iodine atoms, makes it a versatile precursor for constructing complex molecules via cross-coupling and nucleophilic substitution reactions. Pharmaceutical, agrochemical, and material science R&D laboratories need this high-purity intermediate for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially in fluorine-containing drug candidates.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the fluorine atom can enhance biological activity and stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing halogenated aromatic cores used in electronic display technologies.
• Cross-Coupling Reactions: The iodine substituent acts as an excellent handle for palladium-catalyzed reactions like Suzuki, Sonogashira, and Negishi couplings to form biaryl structures.
• Ligand & Catalyst Development: Utilized in the preparation of specialized ligands for catalysis and molecular recognition studies.
• Chemical Research & Development: A valuable reagent for exploring new synthetic methodologies and constructing complex molecular architectures in academic and industrial settings.

Basic Information

Product Name	Benzene, 2-Fluoro-4-Iodo-1-Methoxy-
CAS No.	3824-21-3
Molecular Formula	C7H6FIO
Molecular Weight	252.03 g/mol
Synonyms	2-Fluoro-4-iodoanisole; 1-Fluoro-2-methoxy-5-iodobenzene; 4-Iodo-2-fluoroanisole; 2-Methoxy-5-iodofluorobenzene; 5-Iodo-2-fluoroanisole; 2-Fluoro-4-iodo-1-methoxybenzene; 2-Fluoro-4-iodophenyl methyl ether
EINECS	Contact for details

Quality Control

Our Benzene, 2-Fluoro-4-Iodo-1-Methoxy- is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and consistency for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.