Description

Dl-2-Fluoro-3-Alanine CAS NO 3821-81-6 is a fluorinated derivative of the amino acid alanine, characterized by the introduction of a fluorine atom at the β-carbon position. This structural modification is of significant interest in medicinal chemistry and drug discovery, as it can dramatically alter the metabolic stability, bioavailability, and binding affinity of peptide-based compounds. It serves as a critical non-natural amino acid building block for researchers and manufacturers developing novel pharmaceuticals, agrochemicals, and biochemical probes.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of fluorinated peptide drugs and protease inhibitors.
• Agrochemical Synthesis: Used in creating advanced, fluorine-containing herbicides and pesticides with enhanced activity and environmental profile.
• Biochemical Research: Employed as a metabolic probe to study enzyme mechanisms and pathways due to the fluorine atom's unique properties.
• Positron Emission Tomography (PET) Tracer Development: Acts as a precursor for F-18 labeled compounds used in medical imaging.
• Peptidomimetics: Incorporated into artificial peptides to improve their stability against enzymatic degradation.
• Ligand and Catalyst Design: Utilized in organometallic chemistry for creating novel chiral ligands and catalysts.

Basic Information

Product Name	Dl-2-Fluoro-3-Alanine
CAS No.	3821-81-6
Molecular Formula	C3H6FNO2
Molecular Weight	107.08 g/mol
Synonyms	DL-3-Fluoroalanine; (±)-3-Fluoro-DL-alanine; 2-Fluoro-3-aminopropanoic acid; 3-Fluoro-DL-α-alanine; β-Fluoro-DL-alanine; DL-β-Fluoroalanine; 3-Fluoroalanine; (RS)-3-Fluoroalanine
EINECS	223-310-4

Quality Control

Our Dl-2-Fluoro-3-Alanine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with detailed specifications for all critical parameters. Our quality commitment supports applications requiring high-purity intermediates for research and cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.