Description

7-Dechloro Griseofulvin is a key chemical intermediate and reference standard derived from the antifungal agent griseofulvin. This compound matters for its role in pharmaceutical research and development, particularly in the synthesis of novel antifungal agents and metabolic studies. It is primarily needed by R&D laboratories, pharmaceutical manufacturers, and analytical service providers focused on antifungal drug discovery and quality control.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of griseofulvin analogs and novel antifungal compounds.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control testing of griseofulvin and related substances.
• Metabolic Studies: Employed in research to investigate the metabolic pathways and degradation products of griseofulvin.
• Biochemical Research: Utilized as a tool compound in studies targeting fungal cell wall synthesis and microtubule function.
• Impurity Profiling: Acts as a specified impurity standard in the pharmaceutical analysis of griseofulvin active pharmaceutical ingredients (APIs) and finished dosage forms.

Basic Information

Product Name	7-Dechloro Griseofulvin
CAS No.	3680-32-8
Molecular Formula	C17H17ClO6
Molecular Weight	352.77 g/mol
Synonyms	7-Deschlorogriseofulvin; NSC 51046; Griseofulvin, 7-dechloro-; (1'S,6'R)-7-Chloro-2',4,6-trimethoxy-6'-methyl-3H,4'H-spiro[1-benzofuran-2,1'-cyclohex[2]ene]-3,4'-dione; 2',4,6-Trimethoxy-6'-methylspiro[benzofuran-2(3H),1'-[2]cyclohexene]-3,4'-dione, 7-chloro-
EINECS	Contact for details

Quality Control

Our 7-Dechloro Griseofulvin is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR, to ensure it meets the high standards required for research and pharmaceutical applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The material is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.